In rare chickenpox case, itchy blisters mushroom into large, rubbery nodules

Those who suffered through chickenpox as kids likely remember the agony of its itchy rash. Oven mitts or snow gloves may have been used to prevent you from inadvertently clawing your skin off, while dips in oatmeal may have offered some temporary relief. But in the end, you just had to endure the full cycle of the rash—from the breakout of the first raised, itchy papules that inflate into fluid-filled blisters that then break and leak, to the scabs that form over the crusty remains. More papules emerge as blisters burst, prolonging the torment. For one 15-year-old in Nepal, the misery continued long after the blisters burst. After some of her crusty scabs began to form scars, they mushroomed into large, uncontrolled skin growths, which were also painful and itchy—and permanent. One on her chest, the largest, measured 4 by 4 cm (about 1.6 by 1.6 inches). These rubbery, firm nodules are called keloids, which are poorly understood skin growths that result from wound healing that goes awry and expands beyond the borders of the original wound. In the teen's case, five large keloids abruptly burst from her chickenpox scars, breaking out in different places on her body—on her right jaw, chest, abdomen, and right flank. The simultaneous emergence of the growths aligns with the diagnosis of "eruptive keloids," an ultra-rare outcome of a chickenpox infection. Only five such cases appear to exist in the scientific literature. Her case, marking the sixth, was published this week in the journal Clinical Case Reports. Read full article Comments